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UNIVERSITY OF WISCONSIN-MADISON
Position Vacancy Listing
PVL# 59487

Working title:

RESEARCH SPECIALIST - PHARMACOLOGY

Official title:

RESEARCH SPECIALIST(T16DN) or ASSOC RESEARCH SPEC(T16FN)

Degree and area of specialization:

B.S./M.S. in the Biological Sciences preferred

Minimum number of years and type of relevant work experience:

Experience working in a molecular/cellular biology laboratory preferred.

Principal duties:

The Research Specialist will assist the Principal Investigator, Assistant Professor Randal S. Tibbetts, on a project to decipher
how mutations in DNA repair proteins manifest as neurodegeneration syndromes in humans. Particular emphasis will be
placed on elucidating a pathway linking the ataxia-telangiectasia-mutated (ATM) protein kinase to the cyclic AMP response
element-binding protein transcription factor and crucial regulator of gene expression. The Research Specialist will be
primarily responsible for the daily execution of experiments relevant to this project. The Research Specialist will receive
instruction from the Principal Investigator and will meet with him once a week to discuss results and plan additional
experiments. Methods to be employed include: mammalian cell transfection, SDS-PAGE and western blotting, real-time PCR,
site-directed mutagenesis, DNA cloning, protein expression and purification. In addition, to these primary responsibilities, the
Research Specialist will also be responsible for ordering and organizing lab supplies and stocks. The Research Specialist will
also help manage one or more undergraduate assistants that perform routine laboratory tasks such as media preparation and
lab maintenance. The Research Specialist will also work closely with graduate students, will present research findings at lab
meetings, and will be encouraged to develop critical thinking skills that may lead to independent research projects. The
potential also exists for travel to scientific meetings.

A criminal background check will be conducted prior to hiring.
A period of evaluation will be required
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Appointment type: Academic Staff
Department(s): SMPH/PHARMACOLOGY
Full time salary rate: Minimum $29,095 ANNUAL (12 months)
Depending on Qualifications
Term: This is a renewable appointment.
Appointment percent: 100%
Anticipated begin date: JULY 12, 2008
Number of positions: 1

TO ENSURE CONSIDERATION

Application must be received by: JULY 07, 2008

HOW TO APPLY:

Unless another application procedure has been specified above, please send resume and cover letter referring to Position Vacancy Listing #59487 to

Gretchen Harvey Phone: 608-265-3735
6152D Medical Science Ctr TTY: 608-263-2473
1300 University Avenue Fax: N/A
Madison WI 53706-1532 Email: gharvey@wisc.edu